Prolia (denosumab) is approved in Canada for the treatment of osteoporosis in men and postmenopausal females. it is given as an injection every 6 months and significantly reduces fracture risk.
Until now, the government coverage through plans such as Trillium or for seniors aged 65 and over, only provided Prolia for women based on specific criteria. As of January 31st, this coverage has been extended to men who are at high risk for a fracture and who have either had adverse effects or lack of efficacy to swallowed osteoporosis medications such as Fosamax or Actonel.
The criteria for coverage for women has also been changed, with the age restriction of being over 75 being removed.
If you have osteoporosis, be sure to discuss this new coverage with your physician to see how it might effect you.
Carolyn Whiskin is the Pharmacy Manager for Charlton Health. Carolyn specializes in the treatment of autoimmune diseases, pharmaceutical compounding, women’s health, pain and smoking cessation. Carolyn has won provincial and national awards for her commitment to patient care and public service.

It is well known that even 1/2 a grapefruit or one glass of juice can reduce an enzyme called cytochrome P450 (CYP 450) by 50% for up to 24 hours. This is important because some medications such as atorvastatin, amlodipine, carbamazepine and one of our newest medications for rheumatoid arthritis, tofacitinib (Xeljanz) need this enzyme to be eliminated from the body. If grapefruit juice is combined with these medications, they could accumulate in the body increasing the potential for adverse effects. Therefore, it is recommended that grapefruit not be ingested with medications requiring this enzyme for processing.